A fearless everywoman stands up to a drug company in this gripping David vs. Goliath story, based on a real-life medical scandal. Irène Frachon (Sidse Babett Knudsen) is a pulmonologist at a hospital in Brest who begins digging into the connection between a widely prescribed diabetes drug and a spate of fatal valve disorders, with help from a research scientist (Benoît Magimel). Soon enough, Irène sets off a media firestorm, making powerful enemies in the pharmaceutical industry who will stop at nothing to suppress her story. Knudsen and writer-director Emmanuelle Bercot have created a memorably eccentric heroine, at once a tireless crusader and compelling human.