Arguably the director’s most popular film pairs Humphrey Bogart and Katharine Hepburn as a crude Canadian skipper and the uptight missionary who joins him on the titular supply boat in 1914 German East Africa. When war breaks out, the two disparate personalities must come together to steer the Queen through treacherous rapids and torpedo a German gunboat. Bogart won his only Oscar as Charlie Allnut, whose enthusiasm for liquor may not have been his toughest acting challenge (among the crew, only he and Huston successfully evaded malaria by finding alternatives to the local drinking water). Hepburn was instructed by Huston to pattern her portrayal on Eleanor Roosevelt, adopting her “society smile” when the going gets tough; she later called this “the best piece of direction” she ever heard.