Mitchum cameos as the local police lieutenant in Scorsese’s brute force update of J. Lee Thompson’s 1962 Southern thriller, which starred Mitchum as the iconic, original antagonist Max Cady.

Robert De Niro stars as Sam “Ace” Rothstein, a small-time gambler who rises through the ranks to run a high-profile casino in 1970s Las Vegas in this spiritual successor to Goodfellas, the eighth collaboration between De Niro and Martin Scorsese.

De Niro delivers one of his most harrowing performances in Michael Cimino’s saga about the Vietnam War and its devastating effects on a tight-knit group of friends from working-class Pennsylvania.

In the wickedly entertaining gangster saga that charts the rise and fall of wiseguy Henry Hill (Ray Liotta), Robert De Niro plays “Jimmy the Gent,” the suave but no less coldblooded mentor to Liotta’s Hill and Joe Pesci’s don’t-call-him-funny loose cannon.

Michael Mann’s epic, high-wire crime drama solidified the filmmaker’s mastery, and marked the first time acting virtuosos Robert De Niro and Al Pacino appeared together onscreen.

Brian De Palma’s frenzied screwball comedy casts De Niro as an aspiring filmmaker and peeping tom who films his neighbors from his Greenwich Village dump, and gets in too deep with some radical activists.

In Martin Scorsese’s iconic cringe comedy, Robert De Niro stars as Rupert Pupkin, a cheerful but deranged comic who aspires to get his big break on the late-night talk show hosted by Jerry Langford (Jerry Lewis).

De Niro’s lasting partnership with Scorsese began with the filmmaker’s breakthrough third feature, an electrifying and unforgettable depiction of small-time thugs in Little Italy that established much of what was to come in both artists’ careers.

In Robert De Niro’s first full-blown action comedy, he plays Jack Walsh, an irritable bounty hunter tasked with retrieving “Duke” (Charles Grodin), a mob accountant in hiding after embezzling millions from his boss Jimmy Serrano (Dennis Farina).

In Sergio Leone’s New York gangster saga drama spanning nearly half a century, Robert De Niro and James Woods play boyhood friends from New York’s Lower East Side who build a doomed bootlegging empire.

Robert De Niro’s Method dedication was taken to new levels with the story of Jake La Motta, a self-destructive boxer whose violence and temper made and broke his career. Winner of the Best Actor Academy Award.

The story of one man’s descent into madness and unspeakable violence, Taxi Driver plays like a feverish nightmare. As rendered by Robert De Niro, Travis Bickle is a character unlike any other.

Although De Niro’s part, playing against Kevin Costner, Andy Garcia, and an Oscar-winning Sean Connery as the eponymous Feds, is quantifiably small, his floridly wicked Al Capone stands as one of his most iconic performances of the 1980s.